DatasetSet_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls
#truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls
#truncNotch_versus_normalThy_repos
Phenotypephenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos
Upregulated in classnormalThy
GeneSetBIOCARTA_MULTI-STEP REGULATION OF TRANSCRIPTION BY PITX2
Enrichment Score (ES)-0.7782707
Normalized Enrichment Score (NES)-1.6070389
Nominal p-value0.014018691
FDR q-value0.16489244
FWER p-Value0.822
Table: GSEA Results Summary



Fig 1: Enrichment plot: BIOCARTA_MULTI-STEP REGULATION OF TRANSCRIPTION BY PITX2   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)		GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1NKD1134028627911.004-0.1134No
2NKD2117073140670.415-0.1668No
3WIF1710018444900.318-0.1779No
4KREMEN211002549330.247-0.1926No
5PPP2R5D4010156 380408 5550112 567016260690.132-0.2488No
6FRAT1780520 212073165340.107-0.2699No
7PROC652027072180.077-0.3038No
8DKK1194021575150.067-0.3172No
9DKK2361043395360.023-0.4250No
10FZD13140215106130.005-0.4827No
11PITX2870537 2690139106650.004-0.4853No
12WNT1478014812651-0.036-0.5907No
13CSNK2A1158057714752-0.239-0.6949No
14DVL15900450 651016214926-0.293-0.6935No
15LRP6513006415329-0.435-0.6992No
16LEF12470082 710028816800-1.509-0.7231Yes
17CREBBP5690035 704005017180-1.936-0.6727Yes
18HDAC1285067017445-2.333-0.6016Yes
19LDB1527060117734-2.886-0.5116Yes
20AXIN13360358 694045117910-3.273-0.4013Yes
21GSK3B536034818027-3.582-0.2766Yes
22CCND2534016718602-8.4300.0008Yes
Table: GSEA details [plain text format]



Fig 2: BIOCARTA_MULTI-STEP REGULATION OF TRANSCRIPTION BY PITX2   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: BIOCARTA_MULTI-STEP REGULATION OF TRANSCRIPTION BY PITX2: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_MULTI-STEP REGULATION OF TRANSCRIPTION BY PITX2